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Define Ventures

Kingmaker TierBased on the data VC Catalog holds.

Kingmaker Tier: 92 out of 100

  • Biotech & therapeutics
  • Care delivery & digital health
  • Health IT
  • Medical devices & diagnostics
  • Mental health & wellness
  • Women's & family health
  • Seed
  • Series A
  • Series B
  • VC
  • B2B
Investor type
VC
Investing status
Activeas of 2026-09-17Source (opens in a new tab)
Headquarters
San Francisco, CA, United States
Assets under management
$800MStated by firm, as of 2026-09-17Source (opens in a new tab)
Latest fund size
$200MSEC amount sold, as of 2021-01-12Source (opens in a new tab)
Funds
8
Legal name
Define Ventures Management, LLC
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Record updated 28 September 2026

About

Define Ventures is one of the largest funds focused on early-stage health tech companies

Investment approach

Thesis
Define Ventures was founded on a simple belief: the future of healthcare will be defined by those who bring together a deep understanding of the healthcare ecosystem paired with a technology-driven mindset.Source (opens in a new tab)
Investing status notes
With $800M under management, Define Ventures partners with the early-stage companies defining healthcare.

Funds

Define Ventures Opportunities I, L.P.
$30MVintage 2021, Opportunity, Closed, SEC amount sold
Define Ventures Fund II, L.P.
$200MVintage 2020, Main fund, Closed, SEC amount sold
Define Ventures Fund I, L.P.
$87.6MVintage 2018, Main fund, Closed, Open-ended, SEC amount sold
Define Ventures Fund III, L.P.
Opportunity
DEFINE VENTURES SELECT I, L.P.
Main fund
Define Ventures Select I, L.P.
Main fund
Define Ventures Fund III, L.P.
Main fund
DEFINE VENTURES OPPORTUNITIES II/III, L.P.
Opportunity

SEC registration

Registered adviser
DEFINE VENTURES MANAGEMENT, LLC
SEC file number
802-114577
Registration
Exempt reporting adviser
Regulatory AUM
$849Mas of 2026-03-27
Private funds reported
6
Principal office
SAN FRANCISCO, CA, United States

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