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Epsilon Health Investors

Kingmaker TierBased on the data VC Catalog holds.

Kingmaker Tier: 83 out of 100

Also known as Epsilon Healthcare Innovation, Epsilon Healthcare Innovation Fund II, LP, EPSILON SPV, EPSILON SPV IV, L.P.

  • Care delivery & digital health
  • Health IT
  • Seed
  • Series A
  • Series B
  • VC
  • B2B
Investor type
VC
Investing status
Activeas of 2026-09-18Source (opens in a new tab)
Headquarters
Washington, DC, United States
Assets under management
$43.2MForm ADV private fund GAV, as of 2026-03-26Source (opens in a new tab)
Latest fund size
$17.6MSEC amount sold, as of 2025-10-31Source (opens in a new tab)
Funds
5
Legal name
Epsilon Health Investors, LLC
Claim, correct or request removal

Record updated 29 September 2026

About

We are a digital-healthcare focused venture capital firm that manages capital on behalf of a group of strategic limited partners and commercial investors. Founded by two healthcare veterans, Steven Epstein and Gregory Epstein of Epstein Becker & Green, P.C., Epsilon draws on decades of experience across healthcare investing, advising, providing regulatory support and board leadership. We leverage our strategic LP base and the deep experience and relationships of our founders and advisors to help our portfolio companies achieve scale.

Investment approach

Thesis
We take a thematic investment approach with a focus on digital health companies that are addressing large pain points and areas of inefficiency in the healthcare system.Source (opens in a new tab)
Leads rounds
Sometimes
Lead policy
Able to lead rounds or invest as a part of a syndicate

Funds

EPSILON SPV IV, L.P.
$3.7MVintage 2023, Main fund, SEC amount sold
Epsilon Healthcare Innovation Fund II, LP
$17.6MVintage 2022, Main fund, SEC amount sold
EPSILON HEALTHCARE OPPORTUNITES FUND, LP
Main fund
EPSILON SPV III, L.P.
SPV
EPSILON SPV I, L.P.
SPV

SEC registration

Registered adviser
EPSILON HEALTH INVESTORS, LLC
SEC file number
802-127807
Registration
Exempt reporting adviser
Regulatory AUM
$43.2Mas of 2026-03-26
Private funds reported
5
Principal office
WASHINGTON DC, DC, United States
SEC CIK
1948657, 1990575

Locations

Headquarters
Washington, DC, United States
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