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New Rhein Healthcare Investors

Kingmaker TierBased on the data VC Catalog holds.

Kingmaker Tier: 82 out of 100

  • Biotech & therapeutics
  • Care delivery & digital health
  • Health IT
  • Medical devices & diagnostics
  • Mental health & wellness
  • Women's & family health
  • Late
  • VC
Investor type
VC
Investing status
Activeas of 2026-09-18Source (opens in a new tab)
Headquarters
Philadelphia, PA, United States
Assets under management
$316MForm ADV private fund GAV, as of 2026-03-30Source (opens in a new tab)
Funds
6
Legal name
New Rhein Healthcare Investors LLC
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Record updated 29 September 2026

About

New Rhein applies a private equity investment approach to life sciences venture capital investing, with a focus on later-stage, de-risked assets with proven clinical safety and efficacy.

Investment approach

Thesis
We believe that product development execution and strategic exits are the most important drivers of investment returns. Our goal is to develop products that deliver important health benefits to patients, compelling economic value to payors, and generate capital gains through strategic exits.Source (opens in a new tab)
Ownership target
take a significant stake in a small number of companies and actively manage their value creation.
Traction requirement
with a focus on later-stage, de-risked assets with proven clinical safety and efficacy.
Investing status notes
New Rhein Funds II and III have invested in six companies developing proprietary drug/device platforms for pain management, BPH, weight management, but also a CDMO or next-generation soft-mist device etc

Funds

NEW RHEIN HEALTHCARE 18 (PARALLEL) SCSP
Parallel
NEW RHEIN HEALTHCARE 18 LP
Main fund
NEW RHEIN HEALTHCARE 2021 PRIVAK
Main fund
NEW RHEIN HEALTHCARE 2021 (LUX) SCSP
Main fund
NEW RHEIN HEALTHCARE 2021 (DE) LP
Main fund
NRHI ALVEUS FUND I, LP
Main fund

SEC registration

Registered adviser
NEW RHEIN HEALTHCARE INVESTORS LLC
SEC file number
801-124768
Registration
SEC registered
Regulatory AUM
$291Mas of 2026-03-30
Private funds reported
6
Principal office
PHILADELPHIA, PA, United States

Locations

Headquarters
Philadelphia, PA, United States
Office
Mechelen, Belgium
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